The St. Lucie County Fire District responded to an early-morning house fire after multiple callers reported hearing a loud explosion.
The fire occurred in the 700 block of 23rd St. just before 12:30 a.m. Friday.
The house, which was unoccupied, was fully involved when crews arrived.
The fire district said the fire began in the southwest corner of the structure. A nearby vacant building sustained some heat damage.
The cause is being investigated.