(CNN) -- The full scale of the destruction wrought by five new tornadoes that plowed through Oklahoma will only be apparent when the sun comes up Saturday morning.
The fresh twisters Friday evening killed at least five people, less than two weeks after a monstrous tornado made rubble of the town of Moore, a suburb of Oklahoma City.
"We really needed a break after last (week), and there's just no rest," said city spokeswoman Kristy Yager.
Among the those killed Friday were a mother and her child, officials said.
At least 71 others were injured statewide.
The storm system swatted down power lines and uprooted trees. It flicked big rigs on their sides, and yanked off part of the terminal roof at Oklahoma City's Will Rogers World Airport.
And, in Moore, it strew salt in the wounds of residents still picking up the pieces from the previous disaster.
"There's damage everywhere," Moore's Mayor Glenn Lewis told Anderson Cooper.
Most of his devastated town was blacked out. The flooded streets made it hard for him to drive the town to search for new ruins among the old ones.
"I can't even get home to see if my house is OK," he said.
Though the tornadoes were not as strong as the EF-5 twister that killed 24 people on May 20, fear drove some people into their cars to flee, ignoring warnings not to drive.
Officials described parts of Interstates 35 and 40 near Oklahoma City as "a parking lot."
"People were actually driving southbound in the northbound lanes to try and get out of the way," said storm chaser Dave Holder.
Those who stayed put ducked for cover.
Players competing in the NCAA women's softball championship in Oklahoma City rode out the storm in an underground garage.
Passengers at Will Rogers sought shelter in the airport's basement. A power outage and debris on the runway had forced the airport to cancel all flights.
The lights flickered back on early Saturday but all morning departures are canceled, spokeswoman Karen Carney said.
Once the terror of the tornadoes passed, Oklahomans faced a new reality: flood waters.
Heavy rains hosed Oklahoma City, with 8 to 11 inches drenching the metro area, Yager said.
One inch of flood water pooled the first floor of City Hall, and apartments in low-lying areas of town were hit harder.
"We've seen widespread flooding throughout the entire 621 square miles," she said.
Flooding stranded five empty city buses and some motorists.
"We saw flooding in areas that we don't see flooding. We were overwhelmed," said police Lt. Jay Barnett.
The impact of the tornadoes wasn't limited to Oklahoma alone. More than 212,000 customers were without power across the Midwest early Saturday morning.
In Illinois, the roof flew off a school gymnasium in Macoupin County. About 25 to 30 homes were damaged, officials said.
In Missouri, Gov. Jay Nixon declared a state of emergency, as the storm front moved into his state, stripping sidings and roofs off homes.
For four hours, the Lambert-St. Louis International Airport in Missouri was closed to remove debris from the runway -- but it reopened early Saturday morning.
In Moore, the howls of civil defense sirens sent storm-weary residents scrambling again.
Candace Looper retreated to her windowless laundry room with her cat, and stacked couch pillows on top of her.
"I've been praying, and I've been singing the 'Lord's Prayer' and singing 'Amazing Grace,' so I'm OK," she told Anderson Cooper.
LaDonna Cobb and her husband, Steve, were with their children at their school on May 20, when the wide tornado demolished the building.
The photo of Steve carrying one of their daughters, with Cobb looking to him with blood in her face, became a symbol of Moore's suffering and resilience.
Friday's tornadoes drove them into a shelter and put fear into their hearts again.
"We're pretty scared here. We're terrified," Cobb told CNN's Piers Morgan.
Going through a second tornado was particular unsettling for their children.
"They were not handling it very well. They were pretty upset," Cobb said.
Once the fury passed, Lewis, the city mayor, took a ride around town in his pickup truck.
"This is unbelievable that it could possibly even hit again," he said.
"We just started picking up (debris) two days ago."
Saturday morning, they'll start all over again.
CNN's Holly Yan, Jake Carpenter, Carma Hassan, Joe Sutton, Jennifer Feldman, Chandler Friedman and Dave Alsup contributed to this report.
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