CLEMSON, S.C. (AP) -- Tajh Boyd threw for three touchdowns and ran for another as No. 21 Clemson opened Atlantic Coast Conference play with a 35-30 victory over No. 11 Florida State on Saturday.
Boyd threw for 344 yards for the Tigers, who reached 4-0 for the first time since 2007. Freshman Sammy Watkins had two of Boyd's scoring passes for 24 and 62 yards as Clemson beat the Seminoles (2-2, 0-1) for the fifth straight time in Death Valley.
Watkins finished with eight catches for 141 yards, his second consecutive 100-yard receiving game.
Florida State played without starting quarterback EJ Manuel, hurt in last week's 23-13 loss to top-ranked Oklahoma. Backup Clint Trickett kept the Seminoles in this, though, with 336 yards and three touchdown passes.
His 9-yard touchdown throw to Kenny Shaw brought Florida State to 35-30 with 7:21 to go. The Seminoles had one final chance, but Trickett was sacked by lineman Rennie Moore on fourth down and the Tigers ran out the clock.
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