WASHINGTON (CNN) -- At times angry and choked with emotion, Secretary of State Hillary Clinton on Wednesday took on Republican critics of her department's handling of the September terrorist attack in Libya that killed the U.S. ambassador and three other Americans, but repeatedly distanced herself from a direct role in specific situations.
"As I have said many times since September 11, I take responsibility," Clinton told the Senate Foreign Relations Committee at the first of two long-anticipated congressional hearings on the attack that became a major issue in the November presidential election.
Conservative Republicans challenged Clinton on the lack of security at the diplomatic compound in Benghazi, where Ambassador Christopher Stevens and three others were killed, as well as the erroneous account provided four days later by U.N. Ambassador Susan Rice that the attack grew spontaneously from a protest over an anti-Islam film produced in the United States.
Sen. Ron Johnson, a tea party backed Wisconsin Republican serving his first term, persistently questioned Clinton about what he called Rice's "purposely misleading" the American people.
"We were misled that there were supposedly protests and something sprang out of that, an assault sprang out of that and that was easily ascertained that that was not the fact," Johnson said, adding that "the American people could have known that within days."
Shouting and gesturing with her arms in frustration, Clinton shot back: "With all due respect, the fact is we had four dead Americans. Was it because of a protest or was it because of guys out for a walk one night decided they'd go kill some Americans?"
Her fists shaking, she continued: "What difference, at this point, does it make? It is our job to figure out what happened and do everything we can to prevent it from ever happening again, senator."
However, she also told the committee she had no direct role in the handling of requests by Stevens and other diplomats for increased security that were denied, saying: "I didn't see those requests. They didn't come to me."
Another conservative Republican, Sen. Rand Paul of Kentucky, told Clinton she should have been fired for not reading cables from Stevens and others in Libya.
At one point, Clinton attempted to wrap up the issue, saying: "If you wish to fault the administration, it's that we didn't have a clear picture, and we probably didn't do as clear a job explaining that we did not have a clear picture, until days later, creating what I think are legitimate questions."
The independent report from the review board said it did not find "that any individual U.S. government employee engaged in misconduct or willfully ignored his or her responsibilities" leading up to the attack. However, one State Department official resigned and three others were placed on administrative leave after the report was released in December.
Later at Wednesday's hearing, in reference to the erroneous talking points by Rice that were aired on September 16, Clinton said she was focused at that time on ensuring the safety of U.S. personnel at other facilities where protests were taking place.
"I was pretty occupied about keeping our people safe, doing what needed to be done," Clinton said, adding "I wasn't involved in the talking points process."
One of the GOP's harshest critics of the administration over the Benghazi attack, Sen. John McCain of Arizona, called Clinton's testimony unsatisfactory.
He said her department had yet to fully disclose all e-mails and other communication from Stevens and others in Benghazi, noting the American people, including the family and loved ones of those killed, deserved full answers.
Critics also complain the assailants remain at large, and Clinton noted that "we continue to hunt the terrorists responsible for the attacks in Benghazi and are determined to bring them to justice."
In her opening statement, Clinton said the Benghazi attack didn't happen in a vacuum but was part of a "broader strategic challenge in North Africa and the wider region."
She defended her department's response, saying there was "timely" and "exceptional" coordination between the State Department and the Pentagon on the night of the attack
"No delays in decision making. No denials of support from Washington or from the military," Clinton said. The review panel's report "said our response saved American lives in real time -- and it did," she added.
Clinton also said she directed the response to the attack from the State Department that night and "stayed in close contact with officials from across our government and the Libyan government."
In addition, Clinton said she immediately took steps to beef up security at